In a study, Phytophthora root rot (PRR) was found to be a serious illness that hampers the development of avocado . To date, all cultivars that have been obtained through traditional breeding are all tolerant of Phytophthora, the authors also said. The authors further noted that Phytophthora cinnamomi Rands are the pathogens of the soil which cause this disease. It is considered that they are one of the most invasive species. It affects all the avocado-producing areas and causes severe damage to the trees. The growing number and effect of these fungi is becoming a more important issue. The scientists and the people concerned have, therefore, found a way to tackle this threat . The use of RNA is involved. In order to suppress the unique gene expression of plants, RNA is used to prevent Phytophthora root rot in avocado plants. Furthermore, it was found that the increasing population is causing a sharp rise in avocado demand worldwide . To meet the rise in order, the farmers or the cultivators are using several elements to increase the avocados’ production. Overuse of the parts is further affecting the plants. The plants are getting affected by pests. Among them, the rot root fungi are the most common form of the problems. The excessive spread of the fungi would destroy the crop and positively affect the crops’ cultivation, so the scientists have discovered several methods that would prevent this. One of the most common ways of avoiding Phytophthora root rot in avocado is RNA splicing. According to a report, Phytophthora root rot in avocado was found to be primarily caused by Phytophthora cinnamomi, a disease of economic significance in avocados worldwide. When fungi are infected and Phytophthora root rot is destroyed, the crops kill the crops and leave co-crops for sale and make money out of them. The economic cost of losses in Australian agriculture was reported to be over AUS$200 million per year in the previous 20 years] [and about US$ 44 million annually in California]. With the help of transgenic rootstocks, RNA silencing is used to improve the resistance of avocado trees. The occurrence of fungal attacks on avocado plants is expected to be decreased.